Vitamin B6 Reduces Lung Cancer Risk

Higher levels of vitamin B6, common amino acid associated with lower risk of lung cancer

An analysis that included nearly 400,000 participants finds that those with higher blood levels of vitamin B6 and the essential amino acid methionine (found in most protein) had an associated lower risk of lung cancer, including participants who were current or former smokers, according to a study in the June 16 issue of JAMA.

“Lung cancer remains the most com­mon cause of cancer death in the world today and is likely to remain so for the near future. It is essential that for lung cancer prevention, any additional evidence about causality does not detract from the importance of reducing the numbers of individuals who smoke tobacco. With this in mind, it is important to recognize that a large proportion of lung cancer cases occur among former smokers, making up the majority in countries where tobacco campaigns have been particularly successful, and a non-trivial number of lung cancer cases oc­cur also among never smokers, particu­larly among women in parts of Asia. Clarifying the role of B vitamins and re­lated metabolites in lung cancer risk is likely therefore to be particularly relevant for former smokers and never smokers,” the authors conclude.

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